The hotel, which is made entirely from steel shipping containers, has 220 rooms and is the official partner of nearby exhibition centre, Eventcity.
The property was built to cater to the increased demand for hotel beds in Trafford City and is already fully booked on its first weekend.
The shipping containers were fully fitted with necessary interiors before being delivered to the site of the hotel.
Peter de la Perrelle, managing director of Tower Hotel Management, operators of the new hotel, said: “This has been a fantastic project for Tower Hotel Management to see through from its conception to launch, and, as the official partner hotel for EventCity, and being next door to Intu Trafford Centre, there’s already a strong demand for beds.
“EventCity has some huge shows coming up this year and we’ve been taking bookings well ahead of opening, with a full house for our first weekend.”